Single nucleotide polymorphisms as tools in human genetics.
نویسندگان
چکیده
The development of detailed single nucleotide polymorphism (SNP) maps of the human genome coupled with high-throughput genotyping technologies may allow us to unravel complex genetic traits, such as multifactorial disease or drug response, over the next few years. Here we describe the current efforts to identify and characterize the large numbers of SNPs required and discuss the practicalities of association studies for the identification of genes involved in complex traits.
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عنوان ژورنال:
- Human molecular genetics
دوره 9 16 شماره
صفحات -
تاریخ انتشار 2000